Information for PSSD patients (mostly German)
Forums
Our international partner organizations
Patient organizations on similar syndromes
Interesting associations, congresses and clubs (list under construction)
TV, radio, podcasts and social media
Libidoverlust durch Antidepressiva? ZDF "Volle Kanne", August 27, 2019.
Accessible from:
https://www.zdf.de/verbraucher/volle-kanne/libidoverlust-durch-antidepressiva-102.html (text only)
https://www.zdf.de/politik/frontal/antidepressiva-experteninterview-bei-vollekanne-100.html (video)
https://www.youtube.com/watch?v=ZLS0W5JxFhc (full video)
Lang anhaltende sexuelle Störungen durch Antidepressiva? ZDF "Frontal21", August 27, 2019. Accessible from:
https://www.presseportal.de/pm/7840/4359195 (text)
https://www.youtube.com/watch?v=vmlw_kXq4yo (full video)
Sex und Depressionen. 1Live "Intimbereich" [Früher "F**k Forward"], September 22, 2020. accessible until October 26, 2022 from:
https://www1.wdr.de/mediathek/audio/1live/f__k-forward/intimbereich-106~_pageaudio-3_type-audio.html
Kein Orgasmus mehr: Sexleben zerstört nach Antidepressiva? WDR/funk "reporter", March 31, 2021. Accessible from:
https://youtu.be/JpQO8F9mFIw
Was tun, wenn die psychische Erkrankung den Sex trübt? Zeit Online "Ist das normal?", September 27, 2021. Accessible from:
https://www.zeit.de/gesundheit/zeit-doctor/2021-09/sexualitaet-gesundheit-psychische-erkrankung-depression-angst-sexsucht-antidepressiva-sexpodcast
Podcast series from PSSD-Canada, accessible at:
https://www.pssdcanada.ca/new-page-3
PSSD - Post-SSRI Sexual Dysfunction. "PsychCast" (Dr. Jan Dreher), April 12, 2022. Accessible from:
https://www.youtube.com/watch?v=qnIzVaCOQvY&t=1s (English subtitles available)
Are antidepressants leaving patients with sexual problems for life? "Medical Minefield", October 1, 2022. Accessible from:
https://omny.fm/shows/the-medical-minefield/221001rmm?in_playlist=medicalminefield#description
Post Antidepressant Sexual Dysfunction. "Radically Genuine": Folge 55, October 6, 2022. Accessible from:
https://open.spotify.com/episode/6OaZMJt3vQNtanhmlQhzWj
Witt-Doerring Interview Series on PSSD
https://www.youtube.com/watch?v=AlcxFGY8JNc&list=PL9wKvL_D79bcDNtEIsfZurZ4_5S82oSI9
Press Publications
gesundheitstipp.ch: "Erst Depression, dann tote Hose" (February 16, 2010)
https://www.gesundheitstipp.ch/artikel/d/erst-depression-dann-tote-hose/
Men's Health: "The Pill That Kills Your Sex Drive" (April 25, 2014)
https://www.menshealth.com/sex-women/antidepressants
Daily Mail: "Depression pills sabotaged my love life: Woman reveals how anti-depressants crushed her libido" (March 20, 2017)
https://www.dailymail.co.uk/health/article-4332998/Can-depression-pills-sabotage-love-life.html
Die Zeit: "'Ich wollte keine Glatze. Die Pille, die der Arzt mir gab, hat mein Leben zerstört'" (February 21, 2018, Post-Finasterid-Syndrom)
https://www.zeit.de/2018/09/finasterid-haarwuchsmittel-erektionsprobleme-klage-pharmaindustrie?utm_referrer=https%3A%2F%2Fnews.google.com%2F
The Guardian: "My life in sex: ‘After taking antidepressants, my genitals felt numb’" (June 8, 2018)
https://www.theguardian.com/lifeandstyle/2018/jun/08/my-life-in-sex-after-taking-antidepressants-my-genitals-felt-numb
Daily Mail: "How depression pills can wreck your sex life: Fresh warning for patients" (June 10, 2019)
https://www.dailymail.co.uk/health/article-7125745/How-depression-pills-wreck-sex-life.html
Psychology Today: "Post-SSRI Sexual Dysfunction Recognized as Medical Condition" (June 14, 2019)
https://www.psychologytoday.com/us/blog/side-effects/201906/post-ssri-sexual-dysfunction-recognized-medical-condition
Deutsche Apotheker Zeitung: "Genitale Taubheit nach SSRI und SNRI" (July 25, 2019)
https://www.deutsche-apotheker-zeitung.de/daz-az/2019/daz-30-2019/genitale-taubheit-nach-ssri-und-snri
Psychology Today: "Protracted Withdrawal Syndrome After Antidepressant Use" (January 4, 2021)
https://www.psychologytoday.com/ca/blog/side-effects/202101/protracted-withdrawal-syndrome-after-antidepressant-use
The Tyee: "Something So Sacred Has Been Taken Away from Me" (November 1, 2021)
https://thetyee.ca/News/2021/11/02/Something-Sacred-Has-Been-Taken-Away/
Beitrag "Post SSRI/SNRI Sexual Dysfunction (PSSD)" auf TheSexMed.com vom (November 15, 2021)
https://thesexmed.com/post-ssri-snri-sexual-dysfunction-pssd/
Daily Mail: "REVEALED: The hidden epidemic of sexual dysfunction which experts blame on SSRI antidepressants" (October 1, 2022)
https://www.dailymail.co.uk/health/article-11269871/The-hidden-epidemic-sexual-dysfunction-experts-blame-SSRI-antidepressants.html
Medical and Academic Resources
Announcements by the European Medicines Agency on persistent side effects caused by SSRI/SNRI:
Publications on PSSD or persistent side effects of (S)SRI/SNRI:
- Bähr S.
Post-SSRI Sexual Dsyfunction: Definition, Symptome, Praxisimplikationen. Fortbildungstelegramm Pharmazie. 2022;16(2):54-82.
- Bahrick AS.
Post SSRI Sexual Dysfunction. ASAP Tablet. 2006;7(3):2-3; 10-11.
- Bahrick AS.
Persistence of Sexual Dysfunction Side Effects after Discontinuation of Antidepressant Medications: Emerging Evidence. Open Psychol J. 2008;1:42-50.
- Bahrick AS, Harris MM.
Sexual Side Effects of Antidepressant Medications: An Informed Consent Accountability Gap. J Contemp Psychother. 2009;39:135-143.
- Bala A, Minh H, Nguyen T, Hellstrom WJG.
Post-SSRI Sexual Dysfunction: A Literature Review. Sex Med Rev. 2018;6(1):29–34.
- Ben-Sheetrit J, Aizenberg D, Csoka A, Weizman A, Hermesh H.
Post-SSRI Sexual Dysfunction: Clinical Characterization and Preliminary Assessment of Contributory Factors and Dose-Response Relationship. J Clin Psychopharmacol. 2015;35(3):273-278.
- Ben-Sheetrit J, Hermon Y, Birkenfeld S, Gutman Y, Csoka AB, Toren P. Estimating the risk of irreversible post-SSRI sexual dysfunction (PSSD) due to serotonergic antidepressants. Ann. Gen. Psychiatry. 2023 Apr 21.
- Bolton JM, Sareen J, Reiss JP.
Genital Anaesthesia Persisting Six Years after Sertraline Discontinuation. J Sex Marital Ther. 2006;32(4):327-330.
- Calabrò RS, De Luca R, Manuli A, Portaro S, Naro A, Quattrini F. Towards Improving Post-SSRI Sexual Dysfunction by Using Nutriceuticals: Lessons from a Case Study. J. Sex Marital Ther. 2019 Feb 13: p. 562-565.
- Coskuner ER, Culha MG, Ozkan B, Kaleagasi EO.
Post-SSRI Sexual Dysfunction: Preclinical to Clinical. Is It Fact or Fiction? Sexual Medicine Reviews. 2018;6(2):217-223.
- Csoka AB, Shipko S.
Persistent Sexual Side Effects after SSRI Discontinuation [letter to the editor]. Psychother Psychosom. 2006;75:187-188.
- Csoka A, Bahrick A, Mehtonen OP.
Persistent Sexual Dysfunction after Discontinuation of Selective Serotonin Reuptake Inhibitors. The Journal of Sexual Medicine. 2008:227-233.
- Diviccaro S, Silvia G, Cioffi L, Falvo E, Caruso D, Melcangi RC.
Paroxetine effects in adult male rat colon: Focus on gut steroidogenesis and microbiota. In: Panzica G, Gotti S, editors. 11th International Meeting Steroids and Nervous System - Torino 2022. Abstract Book. 2022; Torino. 109-110.
- Eckert N.
Antidepressiva: Ungeahnte Effekte der Therapie. Dtsch Arztebl. 2019;116(50):2346-2349.
- Farnsworth KD, Dinsmore , Wallace W.
Persistent sexual dysfunction in genitourinary medicine clinic attendees induced by selective serotonin reuptake inhibitors. International Journal of STD & AIDS. 2009;20(1):68-69.
- Genitale Taubheit nach SSRI und SNRI. Dtsch Apoth Ztg. 2019(30):20.
- Giatti S, Diviccaro S, Panzica G, Melcangi RC.
Post-finasteride syndrome and post-SSRI sexual dysfunction: two sides of the same coin? Endocrine. 2018;61(2):180-193.
- Giatti S, Diviccaro S, Cioffi L, Falvo E, Caruso D, Melcangi RC.
Effects of paroxetine treatment and its withdrawal on neurosteroidogenesis. Psychoneuroendocrinology. 2021;132 Suppl 11.
- Giatti S, DiDomizio A, Diviccaro S, Cioffi L, Marmorini I, Falvo E, et al.
Identification of a novel off-target of paroxetine: Possible role in sexual dysfunction induced by this SSRI antidepressant drug. J Mol Struct. 2022 Nov.
- Gouvêa TS, Morimoto HK, de Faria MJSS, Moreira EG, Gerardin DCC.
Maternal exposure to the antidepressant fluoxetine impairs sexual motivation in adult male mice. Pharmacol Biochem Behav. 2008;90(3):416-419.
- Healy D. Citizen petition: Sexual side effects of SSRIs and SNRIs. Int. J. Risk Saf. Med. 2018 Jun 4: p. 135-147.
- Healy D, Le Noury J, Mangin D. Enduring sexual dysfunction after treatment with antidepressants, 5α-reductase inhibitors and isotretinoin: 300 cases. Int. J. Risk Saf. Med. 2018 Jun 4: p. 125-134.
- Healy D, Le Noury J, Mangin D. Post-SSRI sexual dysfunction: Patient experiences of engagement with healthcare professionals. Int J Risk Saf Med. 2019 Sep 21: p. 167-178.
- Healy D. Post-SSRI Sexual Dysfunction & Other Enduring Sexual Dysfunctions. Epidemiol. Psychiatr. Sci. 2019 Sep 23: p. 1-2.
- Healy D, LaPalme J, Levin M. Post-SSRI Sexual Dysfunction: A Bioelectric Mechanism? Bioelectricity. 2020 Mar 18.
- Healy D, Reisman Y. ISSM Webinar on Post-SSRI Sexual Dysfunction [Zoom-Webinar]. Zoom; 2021 [cited 2021 7 31. Available from:
https://www.youtube.com/watch?v=yFxMeoaIc3c.
- Healy D, Bahrick A, Bak M, Barbato A, Calabrò RS, Chubak BM, et al. Diagnostic criteria for enduring sexual dysfunction after treatment with antidepressants, finasteride and isotretinoin. Int J Risk Saf Med. 2021 Oct 26.
- Healy D, Mangin D, Lochhead J. Development and persistence of patient-reported visual problems associated with serotonin reuptake inhibiting antidepressants. Int J Risk Saf Med. 2022 Feb 22: p. 37-47.
- Hengartner MP, Schulthess L, Sorensen A, Framer A. Protracted withdrawal syndrome after stopping antidepressants: a descriptive quantitative analysis of consumer narratives from a large internet forum. Ther Adv Psychopharmacol. 2020 Dec 24: p. 1-13.
- Hogan C, Le Noury J, Healy D, Mangin D. One hundred and twenty cases of enduring sexual dysfunction following treatment. Int J Risk Saf Med. 2014: p. 109-116.
- Institut für Arzneimittelinformation. EMA: Lang anhaltende sexuelle Störungen durch SSRI und SNRI. a-t. 2019 Jul 05.
- Kanherkar RR, Getachew B, Ben-Sheetrit J, Varma S. The Effect of Citalopram on Genome-Wide DNA Methylation of Human Cells. Int J Genomics. 2018 Jul 25.
- Kauffman RP, Murdock A. Prolonged Post-Treatment Genital Anesthesia and Sexual Dysfunction Following Discontinuation of Citalopram and the Atypical Antidepressant Nefazodone. Open Womens Health J. 2007 Dec: p. 1-3.
- Lane C. Protracted Withdrawal Syndrome After Antidepressant Use. Psychol. Today. 2021 Jan 04.
- Lorenz TK. Antidepressant Use During Development May Impair Women's Sexual Desire in Adulthood. J Sex Med. 2020 Mar: p. 1-7.
- De Luca R, Bonanno M, Manuli A, Calabrò RS.
Cutting the First Turf to Heal Post-SSRI Sexual Dysfunction: A Male Retrospective Cohort Study. Medicines. 2022 Sep 01.
- Maciag D, Simpson KL, Coppinger D, Lu Y, Wang Y, Lin RCS, et al. Neonatal Antidepressant Exposure has Lasting Effects on Behavior and Serotonin Circuitry. Neuropsychopharmacology. 2006 Jan: p. 47-57.
- Micka B. Janusköpfige SSRI: Gehören sexuelle Dysfunktion, Osteoporose und Krebs zur dunklen Seite der Stimmungsaufheller? Medscape. 2019 Dec 13.
- Moncrieff J. Persistent adverse effects of antidepressants. Epidemiol Psychiatr Sci. 2020 Sep 23.
- Netherlands Pharmacovigilance Centre Lareb. Netherlands Pharmacovigilance Centre Lareb. [Online].; 2012 [cited 2021 10 11. Available from:
https://databankws.lareb.nl/Downloads/KWB_2012_3_SSRI.pdf.
- Patacchini A, Cosci F. A Paradigmatic Case of Postselective Serotonin Reuptake Inhibitors Sexual Dysfunction or Withdrawal After Discontinuation of Selective Serotonin Reuptake Inhibitors? J Clin Psychopharmacol. 2020 1/2: p. 93-95.
- Patacchini A, Cosci F. Exposure to serotonin selective reuptake inhibitors or serotonin noradrenaline reuptake inhibitors and sexual dysfunction: Results from an online survey. Int J Risk Saf Med. 2021 Aug 13: p. 229-242.
- Raj S.
Post-SSRI Sexual Dysfunction: Exploration of the Sexual Domains and Symptoms. Utrecht:2020.
- Rayen I, Steinbusch HWM, Charlier TD, Pawluski JL.
Developmental fluoxetine exposure and prenatal stress alter sexual differentiation of the brain and reproductive behavior in male rat offspring. Psychoneuroendocrinology. 2013;38(9):1618-1629.
- Reisman Y.
Sexual Consequences of Post-SSRI Syndrome. Sex Med Rev. 2017;5(4):429-433.
- Reisman Y. Are There Any Sex/Gender Differences in Post-Selective Serotonin Reuptake Inhibitors (SSRI) Sexual Dysfunction (PSSD)? Curr Sex Health Rep. 2019(11):237–242.
- Reisman Y.
Post-SSRI sexual dysfunction. Brit Med J. 2020;368:m754.
- Reisman Y. Explanatory Processes and Diagnosis of PSSD: What do we still need to know?. International Society of Sexual Medicine; 2021 [cited 2021 Jul 31]. Available from:
https://www.youtube.com/watch?v=yFxMeoaIc3c.
- Reisman Y, Pfaus JG, Lowenstein L.
Post-SSRI Sexual Dysfunction (PSSD). In: Reisman Y, Lowenstein L, Tripodi F, editors. Textbook of Rare Sexual Medicine Conditions. Cham: Springer; 2022. p. 51-63.
- Reisman Y, Jannini TB, Jannini EA.
Post-Selective Serotonin Reuptake Inhibitor Sexual Dysfunctions (PSSD): Clinical Experience with a Multimodal Approach. J Men's Health. 2022 Aug 01.
- Rothmore J.
Antidepressant-induced sexual dysfunction. Med J Aust. 2020;212(7):329-334.
- Al Shaban Rodríguez OWMA, de Morales Gómez-Moreno EÁ, Fernández Fernández J, Fresno García C, del Mar Fernández Fernández M. Sexuálne dysfunkcie pretrvávajúce tratamiento con inhibidores selectivos de la recaptación de serotonina. Psiquiatría Biológica. 2017: p. 70-72.
- Simonsen AL, Danborg PB, Gøtzsche PC.
Persistent sexual dysfunction after early exposure to SSRIs: Systematic review of animal studies. Int J Risk Saf Med. 2016;28(1):1-12.
- Spindler PE.
Palinopsie nach Absetzen von Venlafaxin [Palinopsia following discontinuation of venlafaxine]. Psychiatr Prax. 2008;35(5):255-257.
- Studt A, Gannon M, Orzel J, Ashley V, Pearlman AM.
Characterizing Post-SSRI sexual dysfunction and its impact on quality of life. Int J Risk Saf Med. 2021;32(4):321-329.
- Vieira ML, Hamada RY, Gonzaga NI, Bacchia AD, Barbieri M, Moreira EG, de Fátima S, Mesquitab P, Gerardina DCC.
Could maternal exposure to the antidepressants fluoxetine and St. John's Wort induce long-term reproductive effects on male rats? Reprod Toxicol. 2013;35:102-107.
- Waldinger MD, van Coevorden RS, Schweitzer DH, Georgiadise J.
Penile anesthesia in Post SSRI Sexual Dysfunction (PSSD) responds to low-power laser irradiation: A case study and hypothesis about the role of transient receptor potential (TRP) ion channels. Eur J Pharmacol. 2015;753:263-268.
- Waraich A, Clemons C, Ramirez R, Yih J, Goldstein S, Goldstein I.
Post-SSRI Sexual Dysfunction (PSSD): Ten Year Retroperspective Chart Review. J Urol. 2020;203(4S):e1179.
Further interesting publications:
- Abler B, Seeringer A, Hartmann A, Grön G, Metzger C, Walter M, et al. Neural Correlates of Antidepressant-Related Sexual Dysfunction: A Placebo-Controlled fMRI Study on Healthy Males Under Subchronic Paroxetine and Bupropion. Neuropsychopharmacology. 2011 May 4: p. 1837-1847.
- Abler B, Kumpfmüller D, Grön G, Walter M, Stingl J, Seeringer A. Neural Correlates of Erotic Stimulation under Different Levels of Female Sexual Hormones. PLoS One. 2013 Feb 13.
- Angst J. Sexual problems in healthy and depressed persons. Int Clin Psychopharmacol. 1998: p. S1-4.
- Aşçibaşi K, Çökmüş FP, Sücüllüoğlu Dikici D, Özkan HM, Alçi D, Altunsoy N, et al. Evaluation of Emotional Adverse Effects of Antidepressants. J Clin Psychopharmacol. 2020 Nov: p. 594-598.
- Atan A, Basar MM, Aydoganli L. Comparison of the Efficacy of Fluoxetine Alone vs. Fluoxetine Plus Local Lidocaine Ointment in the Treatment of Premature Ejaculation. Archivos españoles de urología. 2000 Nov: p. 856-858.
- Aydemir EO, Aslan E, Yazici MK. SSRI Induced Apathy Syndrome. Arch psychiatry behav sci. 2018;8(2):63-70.
- Babb JA, Linnros SE, Commons KG. Evidence for intact 5-HT1A receptor-mediated feedback inhibition following sustained antidepressant treatment in a rat model of depression. Neuropharmacology. 2018 Oct: p. 139–147.
- Balon R. SSRI-Associated Sexual Dysfunction. Am J Psychiatry. 2006 Sep: p. 1504-1509.
- Beeder LA, Samplaski MK. Effect of antidepressant medications on semen parameters and male fertility. Int J Urol. 2020: p. 39-46.
- Bishop JR, Moline J, Ellingrod VL, Schultz SK, Clayton AH. Serotonin 2A - 1438 G/A and G-Protein Beta3 Subunit C825T Polymorphisms in Patients with Depression and SSRI-Associated Sexual Side-Effects. Neuropsychopharmacology. 2006 May 10: p. 2281–2288.
- Bishop JR, Ellingrod VL, Akroush M, Moline J. The Association of Serotonin Transporter Genotypes and Selective Serotonin Reuptake Inhibitor (SSRI) Associated Sexual Side Effects: Possible Relationship to Oral Contraceptives. Hum Psychopharmacol. 2009 Apr: p. 207-215.
- Bossini L, Fortini V, Casolaro I, Caterini C, Koukouna D, Cecchini F, et al. Sexual dysfunctions, psychiatric diseases and quality of life: a review. Psychiatr Pol. 2014: p. 715-726.
- Choi JB, Cho KJ, Kim JC, Pae CU, Koh JS. An open-label, single-arm pilot study to evaluate the efficacy of daily low dose tadalafil on depression in patients with erectile dysfunction. Transl Androl Urol. 2019: p. 501-506.
- Clément P, Laurin M, Compagnie S, Facchinetti P, Bernabé J, Alexandre L, et al. Effect of Dapoxetine on Ejaculatory Performance and Related Brain Neuronal Activity in Rapid Ejaculator Rats. The Journal of Sexual Medicine. 2012 Oktober: p. 2562-2573.
- Clément P, Bernabé J, Gengoc P, Denys P, Laurin M, Alexandre L, et al. Supraspinal Site of Action for the Inhibition of Ejaculatory Reflex by Dapoxetine. European Urology. 2007 März: p. 825-832.
- Commons KG, Linnros SE. Delayed Antidepressant Efficacy and the Desensitization Hypothesis. ACS Chem. Neurosci. 2019 Feb 19: p. 3048–3052.
- Cosci F, Chouinard G, Chouinard VA, Fava GA. The Diagnostic clinical Interview for Drug Withdrawal 1 (DID-W1) – New Symptoms of Selective Serotonin Reuptake Inhibitors (SSRI) or Serotonin Norepinephrine Reuptake Inhibitors (SNRI): inter-rater reliability. Rivista di psichiatria. 2018: p. 95-99.
- El-Din MM, Senbel AM, Daabees TT, Sharabi FM. Peripheral Modulation of Dopaminergic Receptors Affects Erectile Responses in Rats. Basic & Clinical Pharmacology & Toxicology. 2006: p. 225-232.
- Fabre LF, Clayton AH, Smith LC, Goldstein IM, Derogatis LR. Association of Major Depression With Sexual Dysfunction in Men. J Neuropsychiatry Clin Neurosci. 2013: p. 308-318.
- Fath R. Ejaculatio praecox: Stiefkind in der urologischen Praxis. Ärztezeitung. 2012 November 9.
- Giuliano F, Allard J. Dopamine and sexual function. International Journal of Impotence Research. 2001: p. 18-28.
- Giuliano F, Allard J. Apomorphine SL (Uprima1): preclinical and clinical experiences learned from the first central nervous system-acting ED drug. International Journal of Impotence Research. 2002: p. 53-56.
- Giuliano F, Bernabé J, Gengo P, Laurin M, Clément P. Acute Dapoxetine Delays Pudendal Motoneuron Reflex Discharges in Anesthetized Rats. In Sexual Medicine Society of North America Annual Meeting New York; 2005; New York.
- Golub MS, Phi CE, Bulleri AM. Regulation of emotional response in juvenile monkeys treated with fluoxetine: MAOA interactions. European Neuropsychopharmacology. 2016 Dezember: p. 1920-1929.
- Goodwin GM, Price J, De Bodinat C, Laredo J. Emotional blunting with antidepressant treatments: A survey among depressed patients. J Affect Disord. 2017 Jun 06: p. 31-35.
- Graf H, Walter M, Metzger CD, Abler B. Antidepressant-related sexual dysfunction - Perspectives from neuroimaging. Pharmacology, Biochemistry and Behavior. 2014 Juni: p. 138-145.
- Graf H, Malejko K, Metzger CD, Walter M, Grön GAB. Serotonergic, Dopaminergic, and Noradrenergic Modulation of Erotic Stimulus Processing in the Male Human Brain. Journal of Clinical Medicine. 2019 März 14: p. 363.
- Henssler J, Heinz A, Brandt L, Bschor T. Absetz- und Rebound-Phänomene bei Antidepressiva. Dtsch Arztebl. 2019 May 16: p. 355-361.
- Hermle L, Simon M, Ruchsow M, Geppert M. Hallucinogen-persisting perception disorder. Therapeutic Advances in Psychopharmacology. 2012: p. 199–205.
- Hicks JK, Bishop JR, Sangkuhl K, Müller D, Ji Y, Leckband SG, et al. Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 andCYP2C19 Genotypes and Dosing of Selective Serotonin Reuptake Inhibitors. Clin Pharmacol Ther. 2015 May 13: p. 127-134.
- Hughes MS, Lessell S. Trazodone-Induced Palinopsia. Arch Ophthalmol. 1990: p. 399-400.
- Ilgın S, Aydoğan-Kılıç G, Baysal M, Kılıç V, Ardıç M, Uçarcan Ş, et al. Toxic Effects of Trazodone on Male Reproductive System via Disrupting Hypothalamic-Pituitary-Testicular Axis and Inducing Testicular Oxidative Stress. Oxidative Med. Cell. Longev. 2018 Jul 29.
- Institut für Arzneimittelinformation. Palinopsie durch Arzneimittel. a-t. 2001: p. 15.
- Institut für Arzneimittelinformation. Nebenwirkungen: SSRI beeinträchtigen Spermienqualität. a-t. 2014 Oct 17: p. 100.
- Institut für Arzneimittelinformation. Persistierende genitale Erregung unter SSRI? a-t. 2018 Mar 16: p. 29-30.
- Kendurkar A, Kaur B. Major Depressive Disorder, Obsessive-Compulsive Disorder, and Generalized Anxiety Disorder: Do the Sexual Dysfunctions Differ? Prim Care Companion J Clin Psychiatry. 2008: p. 299-305.
- Kennedy SH, Dickens SE, Eisfeld BS, Bagby RM. Sexual dysfunction before antidepressant therapy in major depression. J Affect Disord. 1999: p. 201-208.
- King VL, Horowitz IR. Vaginal Anesthesia Associated with Fluoxetine Use [Letter to the Editor]. Am J Psychiatry. 1993: p. 984-985.
- Kumar K, Sharma VL, Tiwari P, Singh D, Maikhuri JP, Gupta G, et al. The spermicidal and antitrichomonas activities of SSRI antidepressants. Bioorg Med Chem Lett. 2006 May 01: p. 2509-2512.
- Measom MO. Penile Anesthesia and Fluoxetine [Letter to the Editor]. Am J Psychiatry. 1991 May: p. 709.
- Montejo AL, Llorca G, Izquierdo JA, Rico-Villademoros F. Incidence of Sexual Dysfunction Associated With Antidepressant Agents: A Prospective Multicenter Study of 1022 Outpatients. J Clin Psychiatry. 2001: p. 10-21.
- Opbroek A, Delgado PL, Laukes C, McGahuey C, Katsanis J. Emotional blunting associated with SSRI-induced sexual dysfunction. Do SSRIs inhibit emotional responses? Int J Neuropsychopharmacol. 2002 Jun: p. 147-151.
- Osis L, Bishop JR. Pharmacogenetics of SSRIs and Sexual Dysfunction. Pharmaceuticals. 2010 Dec: p. 3614-3628.
- Price J, Cole V, Goodwin GM. Emotional side-effects of selective serotonin reuptake inhibitors: qualitative study. Br J Psychiatry. 2009: p. 211-217.
- Price J, Cole V, Dolla H, Goodwin GM. The Oxford Questionnaire on the Emotional Side-effects of Antidepressants (OQuESA): Development, validity, reliability and sensitivity to change. J Affect Disord. 2012 Sep: p. 66-74.
- Raap DK, Garcia F, Muma NA, Wolf WA, Battaglia G, van de Kar LD. Sustained Desensitization of Hypothalamic 5-Hydroxytryptamine1A Receptors after Discontinuation of Fluoxetine: Inhibited Neuroendocrine Responses to 8-Hydroxy-2-(Dipropylamino)Tetralin in the Absence of Changes in Gi/o/z Proteins. J Pharmacol Exp Ther. 1999 Feb: p. 561-567.
- Rao D, Zajecka J, Skubiak T. The Modified Rush Sexual Inventory: Preliminary psychometric findings. Psychiatry Res. 2005: p. 175-181.
- Rappek NAM, Sidi H, Kumar J, Kamarazaman S, Das S, Masiran R, et al. Serotonin Selective Reuptake Inhibitors (SSRIs) and Female Sexual Dysfunction (FSD): Hypothesis on its Association and Options of Treatment. Current Drug Targets. 2018 September 1: p. 1352-1358.
- Rizzo SJS, Pulicicchio C, Malberg JE, Andree TH, Stack GP, Hughes ZA, et al. 5-HT1A receptor antagonism reverses and prevents fluoxetine-induced sexual dysfunction in rats. Int J Neuropsychopharmacol. 2009 Sep: p. 1045-1053.
- Safarinejad MR. Sperm DNA Damage and Semen Quality Impairment After Treatment With Selective Serotonin Reuptake Inhibitors Detected Using Semen Analysis and Sperm Chromatin Structure Assay. J Urol. 2008 Nov: p. 2124-2128.
- Santana Y, Montejo AL, Martín J, LLorca G, Bueno G, Blázquez JL. Understanding the Mechanism of Antidepressant-Related Sexual Dysfunction: Inhibition of Tyrosine Hydroxylase in Dopaminergic Neurons after Treatment with Paroxetine but Not with Agomelatine in Male Rats. Journal of Clinical Medicine. 2019 Jan 23: p. 133.
- Schimelpfening N. Can Antidepressants Make You Feel Emotionally Numb? verywellmind. 2019 Jun 19.
- Seidman SN, Roose SP, Menza MA, Shabsigh R, Rosen RC. Treatment of Erectile Dysfunction in Men With Depressive Symptoms: Results of a Placebo-Controlled Trial With Sildenafil Citrate. Am J Psychiatry. 2001 Oct: p. 1623–1630.
- Simmons AN, Arce E, Lovero KL, Stein MB, Paulus MP. Subchronic SSRI administration reduces insula response during affective anticipationin healthy volunteers. Int J Neuropsychopharmacol. 2009 Jun 23: p. 1009-1020.
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